NEW RANGE OF CROSS-LINKED HYALURONIC ACIDS FROM IT PHARMA

BEAUTY IS BASED ON THE PRINCIPLE OF HARMONY. HARMONY ALWAYS CAPTIVATES US, TRANSMITS SERENITY, PEACE OF THE SENSES. BECAUSE BECAUSE BEAUTY IS IN BALANCE.

BEAUTY IS BASED ON THE PRINCIPLE OF HARMONY. HARMONY ALWAYS CAPTIVATES US, TRANSMITS SERENITY, PEACE OF THE SENSES. BECAUSE BECAUSE BEAUTY IS IN BALANCE.

THE ORIGIN OF

CROSSLINKING PROCESS

In the HARMONIE hyaluronic acid line production process, the residual amount of BDDE is under 1 p.p.m, less than half the maximum limit authorised by the FDA.

This guarantees a product with an extremely high safety index. 99.99% of the processed BDDE (butanediol diglycidyl ether) is non-toxic to the skin. With this process it is possible to successfully fill the skin thanks to the HARMONIE formula, an extremely stable cross-linked acid.

FRAGMENTATION OF HARMONIE

To integrate the hyaluronic acid gel, we use titanium and niobium blades in order to help prevent the presence of heavy metal particles in the gel and to achieve maximum product purity.

STABILISATION

The HARMONIE line is stabilised through a buffer system. This maximises the physiological stability of the hydrogel between pH 7.2 and 7.4.

Ions Na + Cl- and K + Cl- in an isotonic concentration provide minimal hygroscopicity, reducing the risk of swelling and subsequent complications in the treatment of the patient. Therefore there is a lower risk of side effects (fibrosis), itching or inflammation.

MOLECULAR SELECTION

1. The dispersion of the hydrogel particles ensures the accuracy of the particle size in each batch. The fraction size of the particles selectively chosen for each product reference in the HARMONIE line makes it possible to successfully improve the application of the filler in different areas of the skin and at different depths.

2. We therefore achieve the rapid adaptation of the tissue to the product, given that the physiological stability of the hydrogel is within the pH range of 7.2-7.4. Likewise, the osmolarity of HARMONIE is close to the physiological values (= 300 mOsmol / kg).

CROSSLINKING PROCESS

In the HARMONIE hyaluronic acid line production process, the residual amount of BDDE is under 1 p.p.m, less than half the maximum limit authorised by the FDA.

This guarantees a product with an extremely high safety index. 99.99% of the processed BDDE (butanediol diglycidyl ether) is non-toxic to the skin. With this process it is possible to successfully fill the skin thanks to the HARMONIE formula, an extremely stable cross-linked acid.

FRAGMENTATION OF HARMONIE

To integrate the hyaluronic acid gel, we use titanium and niobium blades in order to help prevent the presence of heavy metal particles in the gel and to achieve maximum product purity.

STABILISATION

The HARMONIE line is stabilised through a buffer system. This maximises the physiological stability of the hydrogel between pH 7.2 and 7.4.

Ions Na + Cl- and K + Cl- in an isotonic concentration provide minimal hygroscopicity, reducing the risk of swelling and subsequent complications in the treatment of the patient. Therefore there is a lower risk of side effects (fibrosis), itching or inflammation.

MOLECULAR SELECTION

1. The dispersion of the hydrogel particles ensures the accuracy of the particle size in each batch. The fraction size of the particles selectively chosen for each product reference in the HARMONIE line makes it possible to successfully improve the application of the filler in different areas of the skin and at different depths.

2. We therefore achieve the rapid adaptation of the tissue to the product, given that the physiological stability of the hydrogel is within the pH range of 7.2-7.4. Likewise, the osmolarity of HARMONIE is close to the physiological values (= 300 mOsmol / kg).

HARMONIE IS BASED ON THREE FUNDAMENTAL PILLARS THAT ALLOW IT TO DEVELOP A UNIQUE SOLUTION WITH GREAT ADVANTAGES IN APPLICATION AND RESULTS.

01/ TOWARDS HARMONY THROUGH SAFETY

The low concentration of BDDE residue present in the entire HARMONIE product line means that each one of its product references offers excellent safety, given that it helps improve patient recovery while reducing the possibility of adverse or side effects on the skin.

Harmonie fillers do not cause an inflammatory response and they have a short recovery period with the least amount of residual BDDE.

HARMONIE LITE 15 MG/ML
HARMONIE MED 17,5 MG/ML
HARMONIE SUP 20 MG/ML

Note

Most dermal HA Fillers contain a high percentage (more than 0.4%) of partially processed BDDE with HA (pendant), which may cause longer rehabilitation period, soreness, and increased swelling.

01/ TOWARDS HARMONY THROUGH SAFETY

The low concentration of BDDE residue present in the entire HARMONIE product line means that each one of its product references offers excellent safety, given that it helps improve patient recovery while reducing the possibility of adverse or side effects on the skin.

Harmonie fillers do not cause an inflammatory response and they have a short recovery period with the least amount of residual BDDE.

HARMONIE LITE 15 MG/ML
HARMONIE MED 17,5 MG/ML
HARMONIE SUP 20 MG/ML

Note

Most dermal HA Fillers contain a high percentage (more than 0.4%) of partially processed BDDE with HA (pendant), which may cause longer rehabilitation period, soreness, and increased swelling.

01/ TOWARDS HARMONY THROUGH SAFETY

The low concentration of BDDE residue present in the entire HARMONIE product line means that each one of its product references offers excellent safety, given that it helps improve patient recovery while reducing the possibility of adverse or side effects on the skin.

Harmonie fillers do not cause an inflammatory response and they have a short recovery period with the least amount of residual BDDE.

Note

Most dermal HA Fillers contain a high percentage (more than 0.4%) of partially processed BDDE with HA (pendant), which may cause longer rehabilitation period, soreness, and increased swelling.

02/ RHEOLOGY: SHAPE MOULDING

1. The HARMONIE line is noted for being an extremely mouldable product, making it possible to work with its three product references at different depths and in different areas.

2. The product offers excellent tissue integration, making it a cross-linked product line that helps achieve complete facial harmony, designed for medical professionals. The risk of fibrosis and granulomas from non-integrated product is practically nil following a minimum post-treatment time.

02/ RHEOLOGY: SHAPE MOULDING

1. The HARMONIE line is noted for being an extremely mouldable product, making it possible to work with its three product references at different depths and in different areas.

2. The product offers excellent tissue integration, making it a cross-linked product line that helps achieve complete facial harmony, designed for medical professionals. The risk of fibrosis and granulomas from non-integrated product is practically nil following a minimum post-treatment time.

02/ RHEOLOGY: SHAPE MOULDING

1. The HARMONIE line is noted for being an extremely mouldable product, making it possible to work with its three product references at different depths and in different areas.

2. The product offers excellent tissue integration, making it a cross-linked product line that helps achieve complete facial harmony, designed for medical professionals. The risk of fibrosis and granulomas from non-integrated product is practically nil following a minimum post-treatment time.

03/ IMPROVED PATIENT EXPERIENCE

1. The HARMONIE line fillers have a physiological pH of 7.2 to 7.4, thereby confirming their safety. This results in the enhanced post-treatment recovery of the patient. When applying the product to the skin, its pH range guarantees less irritation or possible patient discomfort.

2. Likewise, the osmolarity of the LITE | MED | SUP fillers is close to the physiological values, reducing the risk of swelling following medical treatment.

3. The combination of these two parameters makes HARMONIE synonymous with excellent quality and extremely high safety.

HARMONIE LITE 15 MG/ML
HARMONIE MED 17,5 MG/ML
HARMONIE SUP 20 MG/ML

A.

Lite | Med | Sup fillers have a physiological pH of 7.2 to 7.4, which con rms its safety.

Note:
pH indicates filler’s overall physiology in relation to tissues.

HARMONIE LITE 15 MG/ML
HARMONIE MED 17,5 MG/ML
HARMONIE SUP 20 MG/ML

B.

Harmonie Lite | Med | Sup osmolality is close to physiological values.

Note:
Osmolality is the reading of salt and active substance concentration within a solution. The parameter is related to the swelling factor and PH. The physiological norm of an isotonic solution is 300 mOsmol per kg. The higher the indication, the higher the risk of swelling after volumetric correction.

03/ IMPROVED PATIENT EXPERIENCE

1. The HARMONIE line fillers have a physiological pH of 7.2 to 7.4, thereby confirming their safety. This results in the enhanced post-treatment recovery of the patient. When applying the product to the skin, its pH range guarantees less irritation or possible patient discomfort.

2. Likewise, the osmolarity of the LITE | MED | SUP fillers is close to the physiological values, reducing the risk of swelling following medical treatment.

3. The combination of these two parameters makes HARMONIE synonymous with excellent quality and extremely high safety.

HARMONIE LITE 15 MG/ML
HARMONIE MED 17,5 MG/ML
HARMONIE SUP 20 MG/ML

A.

Lite | Med | Sup fillers have a physiological pH of 7.2 to 7.4, which con rms its safety.

Note:
pH indicates filler’s overall physiology in relation to tissues.

HARMONIE LITE 15 MG/ML
HARMONIE MED 17,5 MG/ML
HARMONIE SUP 20 MG/ML

B.

Harmonie Lite | Med | Sup osmolality is close to physiological values.

Note:
Osmolality is the reading of salt and active substance concentration within a solution. The parameter is related to the swelling factor and PH. The physiological norm of an isotonic solution is 300 mOsmol per kg. The higher the indication, the higher the risk of swelling after volumetric correction.

03/ IMPROVED PATIENT EXPERIENCE

1. The HARMONIE line fillers have a physiological pH of 7.2 to 7.4, thereby confirming their safety. This results in the enhanced post-treatment recovery of the patient. When applying the product to the skin, its pH range guarantees less irritation or possible patient discomfort.

2. Likewise, the osmolarity of the LITE | MED | SUP fillers is close to the physiological values, reducing the risk of swelling following medical treatment.

3. The combination of these two parameters makes HARMONIE synonymous with excellent quality and extremely high safety.

A.

Lite | Med | Sup fillers have a physiological pH of 7.2 to 7.4, which con rms its safety.

Note:
pH indicates filler’s overall physiology in relation to tissues.

B.

Harmonie Lite | Med | Sup osmolality is close to physiological values.

Note:
Osmolality is the reading of salt and active substance concentration within a solution. The parameter is related to the swelling factor and PH. The physiological norm of an isotonic solution is 300 mOsmol per kg. The higher the indication, the higher the risk of swelling after volumetric correction.

THE IT PHARMA PRODUCT LINE

HARMONIE

Suitable for the treatment of fine lines and a general improvement of the quality
of the skin and lips hydration.

HA CONCENTRATION: 15 MG/ML

AREAS TO BE TREATED: Fine lines, Forehead, Bar code, Neck and hands and Lips hydratation.

HARMONIE

Suitable for the treatment of fine lines and a general improvement of the quality
of the skin and lips hydration.

HA CONCENTRATION: 15 MG/ML

AREAS TO BE TREATED: Fine lines, Forehead, Bar code, Neck and hands and Lips hydratation.

HARMONIE

Suitable for  filling moderate wrinkles and for lip profiling. Optimal results in nose harmonization and periorbital rejuvenation.

HA CONCENTRATION: 17,5 MG/ML

AREAS TO BE TREATED: Nasolabial folds, Filling moderate wrinkles, Nose harmonization, Lip profiling and Periorbital rejuvenation.

HARMONIE

Suitable for  filling moderate wrinkles and for lip profiling. Optimal results in nose harmonization and periorbital rejuvenation.

HA CONCENTRATION: 17,5 MG/ML

AREAS TO BE TREATED: Nasolabial folds, Filling moderate wrinkles, Nose harmonization, Lip profiling and Periorbital rejuvenation.

HARMONIE

Recommended for deep wrinkles and the correction of facial contour and lip augmentation and volumization.

HA CONCENTRATION:  20 MG/ML

AREAS TO BE TREATED: Correction of facial volume, Filling of deep wrinkles, Remodelling of jaw line and chin,  Masculinization and Lip volumization.

HARMONIE

Recommended for deep wrinkles and the correction of facial contour and lip augmentation and volumization.

HA CONCENTRATION:  20 MG/ML

AREAS TO BE TREATED: Correction of facial volume, Filling of deep wrinkles, Remodelling of jaw line and chin,  Masculinization and Lip volumization.